HSCI-280 Biochemistry and Molecular Cell Biology of Health and Disease
Spring for 2017-2018
This course will build upon concepts learned in prerequisite courses in chemistry and human biology, aiming toward a deeper understanding of the biochemical, molecular and cellular processes that underlie human health and disease. It will prepare the student for advanced study in genetics, cell biology, biochemistry and immunology. Topics include structure, function and kinetics of macromolecules, cell structure, membranes and compartmentalization, signaling, growth control, and cell organization and interaction. Each topic will be presented with emphasis on its explanatory value with respect to disease states and therapeutic approaches. In the laboratory, students will learn experimental techniques in biochemistry and molecular cell biology and gain experience in reading and writing scientific articles.

Course Objectives
This course will improve students’ abilities to:
1. Describe the parts of a cell, how they work and understand the limits of our current knowledge.
2. Discuss the molecular mechanisms of diseases and how knowledge of normal molecular cell biology and biochemistry enables us to understand disease and develop potential therapies.
3. Discuss how molecular cell biologists ask and answer questions experimentally. 4. Analyze scientific data accumulated in the laboratory and recorded in the laboratory notebook.
5. Communicate science in the format of a scientific paper.
Credits: 4
Prerequisites: HSCI 101 and 102 and Gen Chem 1 and 2
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